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Functional assays to determine the significance of two common XPC 3'UTR variants found in bladder cancer patients
BACKGROUND: XPC is involved in the nucleotide excision repair of DNA damaged by carcinogens known to cause bladder cancer. Individuals homozygous for the variant allele of XPC c.1496C > T (p.Ala499Val) were shown in a large pooled analysis to have an increased bladder cancer risk, and we found tw...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3142493/ https://ncbi.nlm.nih.gov/pubmed/21689419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-84 |
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