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Translocation of an antibody transgene requires AID and occurs by interchromosomal switching to all switch regions except the mu switch region
Immunoglobulin (Ig) class switch recombination (CSR) occurs most often by intrachromosomal recombinations between switch (S) regions located on a single chromosome, but can also occur by interchomosomal recombinations between Ig heavy chain (Igh) S regions located on chomosomal homologs. Interchromo...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3142474/ https://ncbi.nlm.nih.gov/pubmed/21469111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201041077 |
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