Polymicrobial sepsis and endotoxemia promote microvascular thrombosis via distinct mechanisms

BACKGROUND: We reported recently that endotoxemia promotes microvascular thrombosis in cremaster venules of wild type mice, but not in mice deficient in toll-like receptor-4 (TLR4) or von Willebrand factor (VWF). OBJECTIVE: To determine whether the clinically relevant model of polymicrobial sepsis i...

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Bibliographic Details
Main Authors:	Patel, Kavita N., Soubra, Said H., Lam, Fong W., Rodriguez, Manuel A., Rumbaut, Rolando E.
Format:	Artigo
Language:	Inglês
Published:	2010
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3142355/ https://ncbi.nlm.nih.gov/pubmed/20345726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2010.03853.x
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Polymicrobial sepsis and endotoxemia promote microvascular thrombosis via distinct mechanisms

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