L3MBTL2 protein acts in concert with PcG protein mediated monoubiquitination of H2A to establish a repressive chromatin structure

We have identified human MBT domain-containing protein L3MBTL2 as an integral component of a protein complex that we termed Polycomb Repressive Complex 1 (PRC1)-like 4 (PRC1L4) given the co-presence of PcG proteins RING1, RING2 and PCGF6/MBLR. PRC1L4 also contained E2F6 and CBX3/ HPlγ known to funct...

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Xehetasun bibliografikoak
Egile Nagusiak: Trojer, Patrick, Cao, Alina R., Gao, Zhonghua, Li, Yan, Zhang, Jin, Xu, Xiaoqin, Li, Guohong, Losson, Regine, Erdjument-Bromage, Hediye, Tempst, Paul, Farnham, Peggy J., Reinberg, Danny
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142354/
https://ncbi.nlm.nih.gov/pubmed/21596310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.04.004
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