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Catechol-O-methyl Transferase and Expression of Schizophrenia in 73 Adults with 22q11 Deletion Syndrome

BACKGROUND: Catechol-O-methyl transferase (COMT) is a candidate gene for schizophrenia with a role in dopamine metabolism, particularly in frontal cortex. COMT is within the region commonly deleted in 22q11 deletion syndrome (22q11DS), a syndrome with high prevalence of schizophrenia. We examined th...

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Bibliographic Details
Main Authors: Bassett, Anne S., Caluseriu, Oana, Weksberg, Rosanna, Young, Donald A., Chow, Eva W.C.
Format: Artigo
Language:Inglês
Published: 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142270/
https://ncbi.nlm.nih.gov/pubmed/17217925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2006.07.038
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