Pain-related sensory innervation in monoiodoacetate-induced osteoarthritis in rat knees that gradually develops neuronal injury in addition to inflammatory pain

BACKGROUND: The exact mechanism of knee osteoarthritis (OA)-associated pain is unclear, whereas mixed evidence of inflammatory pain and neuropathic pain has been noted. We aimed to investigate pain-related sensory innervation in a monoiodoacetate (MIA)-induced model of OA. METHODS: Sixty of seventy...

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Detalhes bibliográficos
Main Authors: Orita, Sumihisa, Ishikawa, Tetsuhiro, Miyagi, Masayuki, Ochiai, Nobuyasu, Inoue, Gen, Eguchi, Yawara, Kamoda, Hiroto, Arai, Gen, Toyone, Tomoaki, Aoki, Yasuchika, Kubo, Takekazu, Takahashi, Kazuhisa, Ohtori, Seiji
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142251/
https://ncbi.nlm.nih.gov/pubmed/21679434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-12-134
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