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Possible involvement of caveolin in attenuation of cardioprotective effect of ischemic preconditioning in diabetic rat heart

BACKGROUND: Nitric oxide (NO) has been noted to produce ischemic preconditioning (IPC)-mediated cardioprotection. Caveolin is a negative regulator of NO, which inhibits endothelial nitric oxide synthase (eNOS) by making caveolin-eNOS complex. The expression of caveolin is increased during diabetes m...

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Detalhes bibliográficos
Main Authors: Ajmani, Preeti, Yadav, Harlokesh N, Singh, Manjeet, Sharma, Pyare L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142229/
https://ncbi.nlm.nih.gov/pubmed/21745415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2261-11-43
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