Melittin restores proteasome function in an animal model of ALS

Amyotrophic lateral sclerosis (ALS) is a paralyzing disorder characterized by the progressive degeneration and death of motor neurons and occurs both as a sporadic and familial disease. Mutant SOD1 (mtSOD1) in motor neurons induces vulnerability to the disease through protein misfolding, mitochondri...

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Autors principals: Yang, Eun Jin, Kim, Seon Hwy, Yang, Sun Choel, Lee, Sang Min, Choi, Sun-Mi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142224/
https://ncbi.nlm.nih.gov/pubmed/21682930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-69
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