Defective Differentiation of Regulatory FoxP3(+) T Cells by Small-Intestinal Dendritic Cells in Patients With Type 1 Diabetes

OBJECTIVE: The gut environment modulates the pathogenesis of type 1 diabetes (T1D), but how it affects autoimmunity toward pancreatic β-cells, a self-tissue located outside the intestine, is still unclear. In the small intestine, lamina propria dendritic cells (LPDCs) induce peripheral differentiati...

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Main Authors: Badami, Ester, Sorini, Chiara, Coccia, Margherita, Usuelli, Vera, Molteni, Laura, Bolla, Andrea Mario, Scavini, Marina, Mariani, Alberto, King, Cecile, Bosi, Emanuele, Falcone, Marika
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2011
Fag:
Immunology and Transplantation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142071/
https://ncbi.nlm.nih.gov/pubmed/21646390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1201
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