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Defective Differentiation of Regulatory FoxP3(+) T Cells by Small-Intestinal Dendritic Cells in Patients With Type 1 Diabetes
OBJECTIVE: The gut environment modulates the pathogenesis of type 1 diabetes (T1D), but how it affects autoimmunity toward pancreatic β-cells, a self-tissue located outside the intestine, is still unclear. In the small intestine, lamina propria dendritic cells (LPDCs) induce peripheral differentiati...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Diabetes Association
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3142071/ https://ncbi.nlm.nih.gov/pubmed/21646390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1201 |
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