ATP-sensitive potassium channel (K(ATP))–dependent regulation of cardiotropic viral infections

The effects of the cellular environment on innate immunity remain poorly characterized. Here, we show that in Drosophila ATP-sensitive potassium channels (K(ATP)) mediate resistance to a cardiotropic RNA virus, Flock House virus (FHV). FHV viral load in the heart rapidly increases in K(ATP) mutant f...

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Huvudupphovsmän: Eleftherianos, Ioannis, Won, Sungyong, Chtarbanova, Stanislava, Squiban, Barbara, Ocorr, Karen, Bodmer, Rolf, Beutler, Bruce, Hoffmann, Jules A., Imler, Jean-Luc
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2011
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141999/
https://ncbi.nlm.nih.gov/pubmed/21719711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108926108
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