Latrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a high-affinity transsynaptic receptor pair with signaling capabilities

Latrophilin 1 (LPH1), a neuronal receptor of α-latrotoxin, is implicated in neurotransmitter release and control of presynaptic Ca(2+). As an “adhesion G-protein-coupled receptor,” LPH1 can convert cell surface interactions into intracellular signaling. To examine the physiological functions of LPH1...

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Detalles Bibliográficos
Main Authors: Silva, John-Paul, Lelianova, Vera G., Ermolyuk, Yaroslav S., Vysokov, Nickolai, Hitchen, Paul G., Berninghausen, Otto, Rahman, M. Atiqur, Zangrandi, Alice, Fidalgo, Sara, Tonevitsky, Alexander G., Dell, Anne, Volynski, Kirill E., Ushkaryov, Yuri A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141932/
https://ncbi.nlm.nih.gov/pubmed/21724987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019434108
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