Small-molecule inhibitor binding to an N-acyl-homoserine lactone synthase

Quorum sensing (QS) controls certain behaviors of bacteria in response to population density. In Gram-negative bacteria, QS is often mediated by N-acyl-l-homoserine lactones (acyl-HSLs). Because QS influences the virulence of many pathogenic bacteria, synthetic inhibitors of acyl-HSL synthases might...

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Autori principali: Chung, Jiwoung, Goo, Eunhye, Yu, Sangheon, Choi, Okhee, Lee, Jeehyun, Kim, Jinwoo, Kim, Hongsup, Igarashi, Jun, Suga, Hiroaki, Moon, Jae Sun, Hwang, Ingyu, Rhee, Sangkee
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141922/
https://ncbi.nlm.nih.gov/pubmed/21730159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103165108
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