Nimesulide inhibits protein kinase C epsilon and substance P in sensory neurons – comparison with paracetamol

In this paper we describe new actions of nimesulide and paracetamol in cultured peripheral neurons isolated from rat dorsal root ganglia (DRG). Both drugs were able to decrease in a dose-dependent fashion the number of cultured DRG neurons showing translocation of protein kinase C epsilon (PKCɛ) cau...

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Hlavní autoři: Vellani, Vittorio, Franchi, Silvia, Prandini, Massimiliano, Moretti, Sarah, Pavesi, Giorgia, Giacomoni, Chiara, Sacerdote, Paola
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2011
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141834/
https://ncbi.nlm.nih.gov/pubmed/21811393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S21931
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