Inhibition of Rho-associated coiled-coil containing protein kinase enhances the activation of epidermal growth factor receptor in pancreatic cancer cells

BACKGROUND: Rho-associated coiled-coil containing protein kinase (Rho-kinase/ROCK) is involved in various cellular functions including cell proliferation, and is generally considered to be oncogenic, while some studies show that ROCK functions as a negative regulator of cancer progression. As a resu...

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Autori principali: Nakashima, Masanori, Adachi, Seiji, Yasuda, Ichiro, Yamauchi, Takahiro, Kawaguchi, Junji, Hanamatsu, Toshimasa, Yoshioka, Takashi, Okano, Yukio, Hirose, Yoshinobu, Kozawa, Osamu, Moriwaki, Hisataka
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141756/
https://ncbi.nlm.nih.gov/pubmed/21722395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-79
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