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Dynamic alterations in the conformation of the Ifng gene region during T helper cell differentiation

Gene expression and silencing in eukaryotic systems can be controlled by regulatory elements acting over a distance. Here, we analyze chromatin conformation of the 24-kb region of the Ifng gene during CD4(+) T helper (Th) cell differentiation. We find that chromatin within this region is a highly fl...

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Autori principali: Eivazova, Elvira R., Aune, Thomas M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC314171/
https://ncbi.nlm.nih.gov/pubmed/14691261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0303919101
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