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Utility of certain nucleophilic aromatic substitution reactions for the assay of pregabalin in capsules

BACKGROUND: Pregabalin (PG) is an anticonvulsant, analgesic and anxiolytic drug. A survey of the literature reveals that all the reported spectrophotometric methods are either don't offer high sensitivity, need tedious extraction procedures, recommend the measurement of absorbance in the near U...

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Autors principals: Walash, Mohamed I, Belal, Fathallah F, El-Enany, Nahed M, El-Maghrabey, Mahmoud H
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141622/
https://ncbi.nlm.nih.gov/pubmed/21711563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-153X-5-36
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