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Energetics of ion conduction through the gramicidin channel

The free energy governing K(+) conduction through gramicidin A channels is characterized by using over 0.1 μs of all-atom molecular dynamics simulations with explicit solvent and membrane. The results provide encouraging agreement with experiments and insights into the permeation mechanism. The free...

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Detalhes bibliográficos
Main Authors: Allen, Toby W., Andersen, Olaf S., Roux, Benoît
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC314148/
https://ncbi.nlm.nih.gov/pubmed/14691245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2635314100
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