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A promoter SNP rs4073T>A in the common allele of the interleukin 8 gene is associated with the development of idiopathic pulmonary fibrosis via the IL-8 protein enhancing mode
BACKGROUND: Interleukin-8 (IL-8) is a potent chemo-attractant cytokine responsible for neutrophil infiltration in lungs with idiopathic pulmonary fibrosis (IPF). The IL-8 protein and mRNA expression are increased in the lung with IPF. We evaluated the effect of single nucleotide polymorphisms (SNPs)...
Gorde:
| Egile Nagusiak: | , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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BioMed Central
2011
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| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3141418/ https://ncbi.nlm.nih.gov/pubmed/21649933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-73 |
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