Dominant-negative C/EBP disrupts mitotic clonal expansion and differentiation of 3T3-L1 preadipocytes

Hormonal induction of growth-arrested 3T3-L1 preadipocytes rapidly activates expression of CCAAT/enhancer-binding protein (C/EBP) β. Acquisition of DNA-binding activity by C/EBPβ, however, is delayed until the cells synchronously enter the S phase of mitotic clonal expansion (MCE). After MCE, C/EBPβ...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Zhang, Jiang-Wen, Tang, Qi-Qun, Vinson, Charles, Lane, M. Daniel
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2003
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314135/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14688407/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307229101
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