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Nicotine self-administration in the rat: effects of hypocretin antagonists and changes in hypocretin mRNA

RATIONALE: The hypocretin (hcrt) system has been implicated in addiction-relevant effects of several drugs but its role in nicotine dependence has been little studied. OBJECTIVES: These experiments examined the role of the hcrt system in nicotine reinforcement. METHODS: Rats were trained for nicotin...

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Detalhes bibliográficos
Main Authors: LeSage, Mark G., Perry, Jennifer L., Kotz, Catherine M., Shelley, David, Corrigall, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141337/
https://ncbi.nlm.nih.gov/pubmed/20177882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-1792-0
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