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Principal component analysis-based filtering improves detection for Affymetrix gene expression arrays

Gene expression array technology has reached the stage of being routinely used to study clinical samples in search of diagnostic and prognostic biomarkers. Due to the nature of array experiments, which examine the expression of tens of thousands of genes simultaneously, the number of null hypotheses...

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Detalles Bibliográficos
Main Authors: Lu, Jun, Kerns, Robnet T., Peddada, Shyamal D., Bushel, Pierre R.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141272/
https://ncbi.nlm.nih.gov/pubmed/21525126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr241
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