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Unidirectional constant rate motion of the ribosomal scanning particle during eukaryotic translation initiation

According to the model of translation initiation in eukaryotes, the 40S ribosomal subunit binds to capped 5′-end of mRNA and subsequently migrates along 5′-UTR in searching for initiation codon. However, it remains unclear whether the migration is the result of a random one-dimensional diffusion, or...

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Hlavní autoři: Vassilenko, Konstantin S., Alekhina, Olga M., Dmitriev, Sergey E., Shatsky, Ivan N., Spirin, Alexander S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141257/
https://ncbi.nlm.nih.gov/pubmed/21415006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr147
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