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Diversity of bacterial type II toxin–antitoxin systems: a comprehensive search and functional analysis of novel families

Type II toxin–antitoxin (TA) systems are generally composed of two genes organized in an operon, encoding a labile antitoxin and a stable toxin. They were first discovered on plasmids where they contribute to plasmid stability by a phenomenon denoted as ‘addiction’, and subsequently in bacterial chr...

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Bibliografiska uppgifter
Huvudupphovsmän: Leplae, Raphaël, Geeraerts, Damien, Hallez, Régis, Guglielmini, Julien, Drèze, Pierre, Van Melderen, Laurence
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141249/
https://ncbi.nlm.nih.gov/pubmed/21422074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr131
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