The pharmacokinetics of PF-734200, a DPP-IV inhibitor, in subjects with renal insufficiency

AIMS: PF-734200 is a potent, selective inhibitor of DPP-IV. This two-part study evaluated the pharmacokinetics (PK) of oral 20 mg PF-734200 in subjects with varying degrees of renal insufficiency or with end-stage renal disease (ESRD) requiring chronic haemodialysis (HD). The study also assessed the...

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Main Authors: Dai, Haiqing, Johnson, Susan L, Terra, Steven G, Marbury, Thomas C, Smith, William B, Alcorn, Harry, Boyd, Rebecca A, Wang, Rong, Nguyen, Tu T
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Science Inc 2011
Ábhair:
Pharmacokinetics
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141189/
https://ncbi.nlm.nih.gov/pubmed/21366665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.03954.x
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