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Aldosterone Regulates Vascular Gene Transcription via Oxidative Stress-Dependent And –Independent Pathways
OBJECTIVE: Aldosterone (Aldo) antagonism prevents cardiovascular mortality by unclear mechanisms. Aldo binds to the mineralocorticoid receptor (MR), a ligand-activated transcription factor, which is expressed in human vascular cells. Here we define the early Aldo-regulated vascular transcriptome and...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3141105/ https://ncbi.nlm.nih.gov/pubmed/21617142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.229070 |
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