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Aging causes collateral rarefaction and increased severity of ischemic injury in multiple tissues

OBJECTIVE: Aging is a major risk factor for increased ischemic tissue injury. Whether collateral rarefaction and impaired remodeling contribute to this is unknown. We quantified the number and diameter of native collaterals, and their remodeling in 3-, 16-, 24-, and 31-months-old mice. METHODS AND R...

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Detalhes bibliográficos
Main Authors: Faber, James E., Zhang, Hua, Lassance-Soares, Roberta M., Prabhakar, Pranay, Najafi, Amir H., Burnett, Mary Susan, Epstein, Stephen E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141082/
https://ncbi.nlm.nih.gov/pubmed/21617137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.227314
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