Genome-Wide Association Study Identifies HLA-DP as a Susceptibility Gene for Pediatric Asthma in Asian Populations

Asthma is a complex phenotype influenced by genetic and environmental factors. We conducted a genome-wide association study (GWAS) with 938 Japanese pediatric asthma patients and 2,376 controls. Single-nucleotide polymorphisms (SNPs) showing strong associations (P<1×10(−8)) in GWAS were further g...

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Bibliografski detalji
Glavni autori: Noguchi, Emiko, Sakamoto, Hiromi, Hirota, Tomomitsu, Ochiai, Kaori, Imoto, Yoshimasa, Sakashita, Masafumi, Kurosaka, Fumitake, Akasawa, Akira, Yoshihara, Shigemi, Kanno, Noriko, Yamada, Yumi, Shimojo, Naoki, Kohno, Yoichi, Suzuki, Yoichi, Kang, Mi-Jin, Kwon, Ji-Won, Hong, Soo-Jong, Inoue, Ken, Goto, Yu-ichi, Yamashita, Fumio, Asada, Takashi, Hirose, Hiroshi, Saito, Ikuo, Fujieda, Shigeharu, Hizawa, Nobuyuki, Sakamoto, Toru, Masuko, Hironori, Nakamura, Yusuke, Nomura, Ichiro, Tamari, Mayumi, Arinami, Tadao, Yoshida, Teruhiko, Saito, Hirohisa, Matsumoto, Kenji
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140987/
https://ncbi.nlm.nih.gov/pubmed/21814517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002170
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