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Elevated expression of c-fos in central nervous system correlates with visceral hypersensitivity in irritable bowel syndrome (IBS): a new target for IBS treatment

BACKGROUND AND AIMS: Although visceral hypersensitivity is a major pathophysiological feature of irritable bowel syndrome (IBS), its molecular mechanisms are still poorly understood. c-fos is a well-established marker of cell activation. Accumulating evidence demonstrates that norepinephrine (NE) sy...

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Detalhes bibliográficos
Main Authors: Zhang, Ru, Zou, Ning, Li, Ji, Lv, Hong, Wei, Jing, Fang, Xiu-Cai, Qian, Jia-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140936/
https://ncbi.nlm.nih.gov/pubmed/21340718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00384-011-1153-4
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