The midregion, nuclear localization sequence, and C terminus of PTHrP regulate skeletal development, hematopoiesis, and survival in mice

The functions of parathyroid hormone-related protein (PTHrP) on morphogenesis, cell proliferation, apoptosis, and calcium homeostasis have been attributed to its N terminus. Evidence suggests that many of these effects are not mediated by the N terminus but by the midregion, a nuclear localization s...

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Detalhes bibliográficos
Main Authors: Toribio, Ramiro E., Brown, Holly A., Novince, Chad M., Marlow, Brandlyn, Hernon, Krista, Lanigan, Lisa G., Hildreth, Blake E., Werbeck, Jillian L., Shu, Sherry T., Lorch, Gwendolen, Carlton, Michelle, Foley, John, Boyaka, Prosper, McCauley, Laurie K., Rosol, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2010
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140789/
https://ncbi.nlm.nih.gov/pubmed/20145205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-147033
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