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Probing mechanical principles of focal contacts in cell–matrix adhesion with a coupled stochastic–elastic modelling framework
Cell–matrix adhesion depends on the collective behaviours of clusters of receptor–ligand bonds called focal contacts between cell and extracellular matrix. While the behaviour of a single molecular bond is governed by statistical mechanics at the molecular scale, continuum mechanics should be valid...
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Main Authors: | , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
The Royal Society
2011
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3140725/ https://ncbi.nlm.nih.gov/pubmed/21632610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2011.0157 |
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