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Probing mechanical principles of focal contacts in cell–matrix adhesion with a coupled stochastic–elastic modelling framework

Cell–matrix adhesion depends on the collective behaviours of clusters of receptor–ligand bonds called focal contacts between cell and extracellular matrix. While the behaviour of a single molecular bond is governed by statistical mechanics at the molecular scale, continuum mechanics should be valid...

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Bibliographic Details
Main Authors: Gao, Huajian, Qian, Jin, Chen, Bin
Format: Artigo
Language:Inglês
Published: The Royal Society 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140725/
https://ncbi.nlm.nih.gov/pubmed/21632610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2011.0157
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