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Luminescent trimethoprim-polyaminocarboxylate lanthanide complex conjugates for selective protein labeling and time-resolved bioassays

Labeling proteins with long-lifetime emitting lanthanide (III) chelate reporters enables sensitive, time-resolved luminescence bioaffinity assays. Heterodimers of trimethoprim (TMP) covalently linked to various cs124-sensitized, polyaminocarboxylate chelates stably retain lanthanide ions and exhibit...

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Detalhes bibliográficos
Main Authors: Reddy, D. Rajasekhar, Pedró Rosa, Laura E., Miller, Lawrence W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140616/
https://ncbi.nlm.nih.gov/pubmed/21619068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200131k
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