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The mammalian mineralocorticoid receptor: tying down a promiscuous receptor
The mineralocorticoid receptor (MR) has been called a promiscuous receptor because its intrinsic affinity for aldosterone, cortisol and corticosterone is similar. Since glucocorticoids circulate in concentrations 100- to 1000-fold those of aldosterone, stoichiometry dictates that MR should be activa...
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| Format: | Artigo |
| Jezik: | Inglês |
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2009
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3140538/ https://ncbi.nlm.nih.gov/pubmed/19648477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2008.045914 |
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