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The mammalian mineralocorticoid receptor: tying down a promiscuous receptor

The mineralocorticoid receptor (MR) has been called a promiscuous receptor because its intrinsic affinity for aldosterone, cortisol and corticosterone is similar. Since glucocorticoids circulate in concentrations 100- to 1000-fold those of aldosterone, stoichiometry dictates that MR should be activa...

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Hlavní autor: Gomez-Sanchez, Elise P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140538/
https://ncbi.nlm.nih.gov/pubmed/19648477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2008.045914
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