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Single-Molecule Studies Reveal that DEAD-Box Protein DDX1 Promotes Oligomerization of HIV-1 Rev on the Rev Response Element

Oligomeric assembly of Rev on the Rev response element (RRE) is essential for the nuclear export of unspliced and singly spliced HIV-1 viral mRNA transcripts. Several host factors, including the human DEAD-box protein DDX1, are also known to be required for efficient Rev function. In this study, spo...

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Bibliographische Detailangaben
Hauptverfasser: Robertson-Anderson, Rae M., Wang, Jun, Edgcomb, Stephen P., Carmel, Andrew B., Williamson, James R., Millar, David P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140434/
https://ncbi.nlm.nih.gov/pubmed/21763499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.04.026
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