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Functional Evolution of BRCT Domains from Binding DNA to Protein
The BRCT domain (BRCA1 C-terminal domain) is an important signaling and protein targeting motif in the DNA damage response system. The BRCT domain, which mainly occurs as a singleton (single BRCT) or tandem pair (double BRCT), contains a phosphate-binding pocket that can bind the phosphate from eith...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Libertas Academica
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3140412/ https://ncbi.nlm.nih.gov/pubmed/21814458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/EBO.S7084 |
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