Human DNA ligase I efficiently seals nicks in nucleosomes
The access to DNA within nucleosomes is greatly restricted for most enzymes and trans-acting factors that bind DNA. We report here that human DNA ligase I, which carries out the final step of Okazaki fragment processing and of many DNA repair pathways, can access DNA that is wrapped about the surfac...
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| Publicado no: | EMBO J |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314012/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11032816/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.20.5492 |
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