Interaction of the Type Iα PIPkinase with phospholipase D: a role for the local generation of phosphatidylinositol 4,5-bisphosphate in the regulation of PLD2 activity

Phosphoinositides are localized in various intracellular compartments and can regulate a number of intracellular functions, such as cytoskeletal dynamics and membrane trafficking. Phospholipase Ds (PLDs) are regulated enzymes that hydrolyse phosphatidylcholine (PtdCho) to generate the putative secon...

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Hauptverfasser: Divecha, Nullin, Roefs, Mieke, Halstead, Jonathan R., D’Andrea, Sabine, Fernandez-Borga, Mar, Oomen, Lauran, Saqib, Kahlid M., Wakelam, Michael J.O., D’Santos, Clive
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2000
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC314009/
https://ncbi.nlm.nih.gov/pubmed/11032811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.20.5440
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