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Structural comparison of dimeric Eg5, Neurospora kinesin (Nkin) and Ncd head–Nkin neck chimera with conventional kinesin

Cryo-electron microscopy and 3D image reconstruction of microtubules saturated with kinesin dimers has shown one head bound to tubulin, the other free. The free head of rat kinesin sits on the top right of the bound head (with the microtubule oriented plus-end upwards) in the presence of 5′-adenylyl...

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Udgivet i:EMBO J
Principais autores: Hirose, Keiko, Henningsen, Ulrike, Schliwa, Manfred, Toyoshima, Chikashi, Shimizu, Takashi, Alonso, Maria, Cross, Robert A., Amos, Linda A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2000
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313998/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11032798/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.20.5308
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