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A dual role for zinc fingers in both DNA binding and zinc sensing by the Zap1 transcriptional activator
The Zap1 transcriptional activator of Saccharomyces cerevisiae controls zinc homeostasis. Zap1 induces target gene expression in zinc-limited cells and is repressed by high zinc. One such target gene is ZAP1 itself. In this report, we examine how zinc regulates Zap1 function. First, we show that tra...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2000
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC313982/ https://ncbi.nlm.nih.gov/pubmed/10899124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.14.3704 |
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