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A dual role for zinc fingers in both DNA binding and zinc sensing by the Zap1 transcriptional activator
The Zap1 transcriptional activator of Saccharomyces cerevisiae controls zinc homeostasis. Zap1 induces target gene expression in zinc-limited cells and is repressed by high zinc. One such target gene is ZAP1 itself. In this report, we examine how zinc regulates Zap1 function. First, we show that tra...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC313982/ https://ncbi.nlm.nih.gov/pubmed/10899124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.14.3704 |
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