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A Miniaturized Technique for Assessing Protein Thermodynamics and Function Using Fast Determination of Quantitative Cysteine Reactivity

Protein thermodynamic stability is a fundamental physical characteristic that determines biological function. Furthermore, alteration of thermodynamic stability by macromolecular interactions or biochemical modifications is a powerful tool for assessing the relationship between protein structure, st...

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Detalhes bibliográficos
Main Authors: Isom, Daniel G., Marguet, Philippe R., Oas, Terrence G., Hellinga, Homme W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139720/
https://ncbi.nlm.nih.gov/pubmed/21387407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22932
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