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Transcriptional termination and coupled polyadenylation in vitro

Using a coupled, in vitro transcription and polyadenylation system we have investigated the molecular mechanism of transcriptional termination by RNA polymerase II (PolII). We showed previously that specific G-rich sequences pause transcription and then activate polyadenylation. We show that physiol...

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Autors principals: Yonaha, Masatomo, Proudfoot, Nick J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC313970/
https://ncbi.nlm.nih.gov/pubmed/10899130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.14.3770
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