Fluoroestradiol (FES) Positron Emission Tomography (PET) Reveals Differences In Pharmacodynamics Of Aromatase Inhibitors, Tamoxifen, And Fulvestrant In Patients With Metastatic Breast Cancer

PURPOSE: To determine, by molecular imaging, how in vivo pharmacodynamics of estrogen-estrogen receptor (ER) binding differ between types of standard endocrine therapy. EXPERIMENTAL DESIGN: The estrogen receptor (ER) has been a highly successful target for breast cancer treatment. ER-directed treatm...

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Detalhes bibliográficos
Main Authors: Linden, Hannah M., Kurland, Brenda F., Peterson, Lanell M., Schubert, Erin K., Gralow, Julie R., Specht, Jennifer M., Ellis, Georgiana K., Lawton, Thomas, Livingston, Robert B., Petra, Philip H., Link, Jeanne M., Krohn, Kenneth A., Mankoff, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139698/
https://ncbi.nlm.nih.gov/pubmed/21750198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-3321
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