Immunodominance of HIV-1 Specific CD8+ T-Cell Responses Is Related to Disease Progression Rate in Vertically Infected Adolescents

BACKGROUND: HIV-1 vertically infected children in the USA are living into adolescence and beyond with the widespread use of antiretroviral drugs. These patients exhibit striking differences in the rate of HIV-1 disease progression which could provide insights into mechanisms of control. We hypothesi...

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Detalhes bibliográficos
Main Authors: Sharp, Elizabeth R., Willberg, Christian B., Kuebler, Peter J., Abadi, Jacob, Fennelly, Glenn J., Dobroszycki, Joanna, Wiznia, Andrew A., Rosenberg, Michael G., Nixon, Douglas F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139570/
https://ncbi.nlm.nih.gov/pubmed/21818255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021135
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