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CD40 signaling in human dendritic cells is initiated within membrane rafts

Despite CD40’s role in stimulating dendritic cells (DCs) for efficient specific T-cell stimulation, its signal transduction components in DCs are still poorly documented. We show that CD40 receptors on human monocyte-derived DCs associate with sphingolipid- and cholesterol-rich plasma membrane micro...

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Bibliografische Detailangaben
Veröffentlicht in:EMBO J
Hauptverfasser: Vidalain, Pierre-Olivier, Azocar, Olga, Servet-Delprat, Christine, Rabourdin-Combe, Chantal, Gerlier, Denis, Manié, Serge
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2000
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313954/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10880443/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.13.3304
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