A Therapeutic SIV DNA Vaccine Elicits T-Cell Immune Responses, But No Sustained Control of Viremia in SIVmac239-Infected Rhesus Macaques

The immunologic and virologic outcome of therapeutic DNA-vaccines administered during antiretroviral therapy (ART) using electroporation with or without (interleukin) IL-2 treatment was evaluated in the SIV-mac239/macaque model. Rhesus macaques inoculated with pathogenic SIVmac239 were treated with...

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Détails bibliographiques
Auteurs principaux: zur Megede, Jan, Sanders-Beer, Brigitte, Silvera, Peter, Golightly, Dawn, Bowlsbey, Abigail, Hebblewaite, Diane, Sites, Deborah, Nieves-Duran, Lourdes, Srivastava, Ranjana, Otten, Gillis R., Rabussay, Dietmar, Zhang, Lei, Ulmer, Jeffrey B., Barnett, Susan W., Donnelly, John J.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2008
Sujets:
Vaccines
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139522/
https://ncbi.nlm.nih.gov/pubmed/18620495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2008.0055
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