GLUTATHIONE PEROXIDASE-1 PLAYS A MAJOR ROLE IN PROTECTING AGAINST ANGIOTENSIN II-INDUCED VASCULAR DYSFUNCTION

Levels of reactive oxygen species, including hydrogen peroxide (H(2)O(2)), increase in blood vessels during hypertension and in response to angiotensin II (Ang II). Although glutathione peroxidases (GPx) are known to metabolize H(2)O(2), the role of GPx during hypertension is poorly defined. We test...

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Autores principales: Chrissobolis, Sophocles, Didion, Sean P., Kinzenbaw, Dale A., Schrader, Laura I., Dayal, Sanjana, Lentz, Steven R., Faraci, Frank M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139513/
https://ncbi.nlm.nih.gov/pubmed/18299484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.107.103572
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