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Converging pathways lead to overproduction of IL-17 in the absence of vitamin D signaling
Multiple pathways converge to result in the overexpression of T(h)17 cells in the absence of either vitamin D or the vitamin D receptor (VDR). CD4(+) T cells from VDR knockout (KO) mice have a more activated phenotype than their wild-type (WT) counterparts and readily develop into T(h)17 cells under...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3139478/ https://ncbi.nlm.nih.gov/pubmed/21697289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxr045 |
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