Adenovirus-specific translation by displacement of kinase Mnk1 from cap-initiation complex eIF4F
Translation of cellular mRNAs involves formation of a cap-binding translation initiation complex known as eIF4F, containing phosphorylated cap-binding protein eIF4E, eIF4E kinase Mnk1, eIF4A, poly(A)-binding protein and eIF4G. Adenovirus is shown to prevent cellular translation by displacing Mnk1 fr...
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| Veröffentlicht in: | EMBO J |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2000
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313943/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10880459/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.13.3465 |
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