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Adenovirus-specific translation by displacement of kinase Mnk1 from cap-initiation complex eIF4F

Translation of cellular mRNAs involves formation of a cap-binding translation initiation complex known as eIF4F, containing phosphorylated cap-binding protein eIF4E, eIF4E kinase Mnk1, eIF4A, poly(A)-binding protein and eIF4G. Adenovirus is shown to prevent cellular translation by displacing Mnk1 fr...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:EMBO J
Hauptverfasser: Cuesta, Rafael, Xi, Qiaoran, Schneider, Robert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2000
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313943/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10880459/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.13.3465
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