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Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair

Two ubiquitin-conjugating enzymes, RAD6 and the heteromeric UBC13–MMS2 complex, have been implicated in post-replicative DNA damage repair in yeast. Here we provide a mechanistic basis for cooperation between the two enzymes. We show that two chromatin-associated RING finger proteins, RAD18 and RAD5...

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Hlavní autoři: Ulrich, Helle D., Jentsch, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC313941/
https://ncbi.nlm.nih.gov/pubmed/10880451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.13.3388
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