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Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair

Two ubiquitin-conjugating enzymes, RAD6 and the heteromeric UBC13–MMS2 complex, have been implicated in post-replicative DNA damage repair in yeast. Here we provide a mechanistic basis for cooperation between the two enzymes. We show that two chromatin-associated RING finger proteins, RAD18 and RAD5...

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Detalhes bibliográficos
Main Authors: Ulrich, Helle D., Jentsch, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC313941/
https://ncbi.nlm.nih.gov/pubmed/10880451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.13.3388
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