Genetic Association between Akt1 Polymorphisms and Alzheimer's Disease in a Japanese Population

A recent paper reported that Aβ oligomer causes neuronal cell death through the phosphatidylinositol-3-OH kinase (PI3K)-Akt-mTOR signaling pathway. Intraneuronal Aβ, a main pathological finding of Alzheimer's disease (AD), is also known as inhibiting activation of Akt. This study aims to invest...

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Main Authors: Shibata, Nobuto, Ohnuma, Tohru, Kuerban, Bolati, Komatsu, Miwa, Baba, Hajime, Arai, Heii
פורמט: Artigo
שפה:Inglês
יצא לאור: SAGE-Hindawi Access to Research 2011
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139182/
https://ncbi.nlm.nih.gov/pubmed/21785701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/762471
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